Senior Research Clinician (Clinical Trials) – (OPTIMIZE Consortium)

Application deadline



Wits Reproductive Health and HIV Institute


Johannesburg , South Africa

Main purpose of the job

To work with the Deputy Executive Director in HIV and related research, including drug optimisation and other clinical trials, clinical work, clinical training, programme oversight, and strategy.


Hugh Solomon Building, Hillbrow, Johannesburg, Charlotte Maxeke Johannesburg Academic Hospital, Yeoville Clinic, and other relevant clinical trials sites.

Key performance areas

  • Support the Deputy Executive Director on all clinical trials and other matters on all studies currently within his scope, as well as to Wits RHI more broadly
  • Lead appropriate studies and relevant sub-studies within the OPTIMIZE arena (treatment optimisation)
  • Provide clinical advice within clinical studies, including designing additional studies
  • Publish relevant research
  • Write grant proposals, protocols and ethics applications in order to fund and carry out research studies
  • Implement research studies in conjunction with relevant internal and external stakeholders
  • Assist with technical requests concerning guidelines, grants, research papers
  • Pro-actively identify strategic areas where clinical studies will be useful within Wits RHI and more broadly (guidelines, conferences, requests for input)
  • Supervise postgraduate degree students as needed
  • Act as a point of contact for the relevant technical area for the DoH, partner organisations, donors and internally where appropriate
  • Communicate with local, regional and international collaborators and stakeholders
  • Participate in monitoring the effectiveness of capacity building interventions and participate in ongoing mentorship programmes initiated by other WHI stakeholders

Required minimum education and training

  • MBBCH degree with specialisation or relevant post-graduate degree in health-related studies
  • A clear track record in managing clinical trials at a senior level
  • HIV clinical experience

Required minimum work experience

  • Minimum of 8 years’ working experience in a similar role

Professional body registration

  • Health Professions Council of South Africa (HPCSA)

Desirable additional education, work experience and personal abilities

  • Certification in HIV Management
  • Good track record in publishing research
  • Experience working in a research and a donor funded organization / NGO or project-based environment and in the public sector
  • Excellent written and verbal communication skills
  • Proficiency in MS Office Suite
  • Experience writing donor proposals and protocols
  • Current or previous membership of clinical or guidelines committees in relevant fields
  • Ordered and systematic in approach to tasks, attention to detail, pro-active, able to exercise discretion and independent decision-making
  • Able to prioritize own work load and work towards deadlines
  • Self-motivated, able to work independently and work as part of a multidisciplinary team
  • Traveling and working outside of normal working hours will be required
  • May be required to work at sites that are under resourced and operate in a highly pressurized environment

Should you be interested in applying for this vacancy, please submit (1) a cover letter (maximum one page) that clearly states which vacancy you are applying for and (2) a detailed CV to: Boitumelo Leduma at [email protected]. Subject Heading of email must read: Advert reference number: TL012 – 2017 and Job Title of position applied for.  Those applicants that do not adhere to the above will not be considered for the respective position applied for.

The Wits RHI will only respond to shortlisted candidates. Candidates who have not been contacted within two weeks of the closing date can consider their applications unsuccessful. In accordance with our Employment Equity goals and plan, preference will be given to suitable applicants from designated groups as defined in the Employment Equity Act 55 of 1998 and subsequent amendments thereto.

Contact personBoitumelo Leduma